New PDF release: Advances in Immunology, Vol. 64

By Frank J. Dixon

ISBN-10: 012022464X

ISBN-13: 9780120224647

Study Institute of Scripps sanatorium, los angeles Jolla. learn within the box. For investigators. 19 individuals, 6 U.S.

Show description

Read Online or Download Advances in Immunology, Vol. 64 PDF

Best biology books

New PDF release: Dictyostelium discoideum Protocols (Methods in Molecular

Dictyostelium discoideum Protocols provides a finished number of state of the art molecular organic protocols for learning D. discoideum, with emphasis on its software within the learn of primary mobile strategies together with sign transduction, chemotaxis, phone motility, cytokinesis, phagocytosis, and features of improvement similar to cellphone sorting, trend formation, and cellphone sort differentiation.

Download e-book for iPad: Capillary Electrophoresis of Proteins and Peptides (Methods by Mark A. Strege, Avinash L. Lagu

Professional educational and pharmaceutical researchers describe their top capillary electrophoresis concepts for protein and peptide research. The authors current state-of-the-art ideas for either capillary coatings and analytic detection through laser-induced fluorescence, for the advance and commercialization of biopharmaceuticals, and for affinity capillary electrophoresis within the evaluate of protein binding, together with using protein cost ladders.

Download e-book for kindle: Plant Bioinformatics: Methods and Protocols by David Edwards

The second one version of this quantity makes a speciality of utilized bioinformatics with particular purposes to plants and version crops. Plant Bioinformatics: tools and Protocols is geared toward plant biologists who've an curiosity in, or requirement for, gaining access to and manipulating large quantities of knowledge being generated through excessive throughput applied sciences.

Additional info for Advances in Immunology, Vol. 64

Example text

MHC-dependent antigen processing and peptide presentation: Providing ligands for lymphocyte activation. Cell 76, 287-299. Germain, R. , and Margulies, D. H. The biochemistry and cell biology of antigen processing and presentation. Annu. Rev. Biochem. 11, 403-450. Goldberg, A. , and Rock, K. L. Proteolysis, proteasomes and antigen presentation. Nature 357, 375-379. Grant, E. , Michlaek, M. , Goldberg, A. , and Rock, K. L. (1995). Rate of antigen degradation by the ubiquitin-proteasome pathway influences MHC class I presentation.

Even if proteasomes work in this capacity, it is still unknown how they are able to recognize sizes and sequences in the given polypeptide antigens to generate the exact epitope peptides. These mechanisms need to be clarified at the molecular level. It is also important to accurately determine if immunoproteasomes indeed contribute to the accelerated antigen processing in response to y I F N stimulation, as was depicted in Fig. 5. Can they indeed be responsible for the production of cryptic epitopes?

Suh, W. , Cohen-Doyle, M. , Peterson, P. , and Williams, D. B. (1994). Interaction of MHC class I molecules with the transporter associated with antigen processing. Science 264, 1322- 1326. , Mott, R. , and Baumeister, W. (1995). The first characterization of a eubacterial proteasome: The 20s complex of Rhodococcus sp. strain NI86/21. Curr. Biol. 5 , 766-774. , Ahn, J. , Chung, C. , DeMartino, C. , Slaughter, C. , and Tanaka, K. (1997). Molecular properties of the proteasome activator PA28 family proteins and yinterferon regulation.

Download PDF sample

Advances in Immunology, Vol. 64 by Frank J. Dixon

by Anthony

Rated 4.12 of 5 – based on 33 votes